Predictive clinical factors for penetration-aspiration in patients with nasopharyngeal carcinoma after radiotherapy

Penetration-aspiration is the most serious complication in patients with nasopharyngeal carcinoma (NPC) after radiotherapy. Radiotherapy has been shown to increase patient's survival rate and life expectancy but it showed side effects such as oropharyngeal dysphagia. It’s related morbidity mortality penetration-aspiration could progress aspiration pneumonia, sepsis, death if not treated properly. Factors suspected be determinants of were location pharyngeal residue, stage NPC, time This primary objective this study was determine clinical factors NPC In a cross sectional, observational analytic study, total 24 obtained consecutive sampling technique. Fiberoptic endoscopic evaluation swallowing (FEES) examination performed on radiotherapy assess residue penetration-aspiration. The Yale Pharyngeal Residue Severity Rating Scale (YPR-SRS) Penetration-Aspiration (PAS) used presence penetration-aspiration, respectively. Statistical analysis multiple logistic regression (p<0,05) Wald statistics find stronger relationship between variables.